PVRL2 抗体
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北京 101111
Quick Overview for PVRL2 抗体 (ABIN1449206)
抗原
See all PVRL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with human CD112 antigen.
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纯化方法
- Protein G agarose
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免疫原
- Recombinant human CD112
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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别名
- CD112 / Nectin 2
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背景
- CD112, also known as Poliovirus Receptor Related 2 (PRR2), is a transmembrane glycoprotein that functions as the receptor for alpha-herpes virus and pseudorabies virus entry into the cell. CD112 has been shown to be identical to Nectin-2, an adhesion protein localized to adherens junctions. CD112 is widely expressed in neuronal, endothelial, and in particular, epithelial cells, where it is found at the intercellular junctions of adjacent cells. Additionally CD112 is detected on hematopoietic progenitors expressing CD34, where it plays a role in the regulation of hematopoietic/endothelial cell interactions. At least two isoforms of CD112 mRNA have been identified.Synonyms: HVEB, Herpes virus entry mediator B, Nectin-2, PRR2, PVRL2, Poliovirus receptor-related protein 2
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基因ID
- 5819
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NCBI登录号
- NP_001036189
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UniProt
- Q92692
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
抗原
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