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CD226 抗体 (FITC)

This anti-CD226 antibody is a 大鼠 单克隆 antibody detecting CD226 in FACS. Suitable for 人.
产品编号 ABIN1449203
发货至: 中国

Quick Overview for CD226 抗体 (FITC) (ABIN1449203)

抗原

See all CD226 抗体
CD226

适用

  • 85
  • 22
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宿主

  • 58
  • 34
  • 6
大鼠

克隆类型

  • 52
  • 45
  • 1
单克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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This CD226 antibody is conjugated to FITC

应用范围

  • 52
  • 39
  • 33
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  • 9
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  • 3
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  • 2
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Flow Cytometry (FACS)

克隆位点

TX25
  • 特异性

    This antibody reacts with human CD226/DNAM-1.

    纯化方法

    Protein G agarose

    免疫原

    Recombinant human CD226/DNAM-1

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, 0.09 % NaN3, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8 °C.
  • 抗原

    CD226

    别名

    CD226 / DNAM1

    背景

    CD226/DNAM-1 (DNAX accessory molecule-1) is a 65 kDa type I transmembrane glycoprotein expressed on the majority of T cells, NK cells, monocytes, and a subset of B-cells. A soluble form (50 kDa) of CD226 is present in normal serum and the supernatant of cultured activated T cells. Ligand binding to CD226 results in phosphorylation of Ser329 and Tyr322, suggesting a role in signal transduction. CD226 acts as an adhesion molecule involved in the binding of certain tumor cells to CTL and NK cells and mediates their cytotoxicity. CD226 also stimulates TNF-α and IFN-γ secretion by alloantigen-specific T cells.Synonyms: DNAM-1, DNAX accessory molecule 1

    基因ID

    10666

    NCBI登录号

    NP_006557

    UniProt

    Q15762

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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