CYBA 抗体 (PE)
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北京 101111
Quick Overview for CYBA 抗体 (PE) (ABIN1449195)
抗原
See all CYBA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes the extracellular peptide portion of primate gp91phox of the Flavocytochrome b558.
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无交叉反应
- 小鼠
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交叉反应 （详细）
- Species reactivity (tested):Human, Monkey.
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纯化方法
- Protein A agarose
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免疫原
- Human cytochrome b-rich fraction
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亚型
- IgG1
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anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 21-120) antibody
CYBA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 128-195) antibodyCYBA 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (N-Term) antibodyCYBA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 WB, ELISA, IF, IHC (fro), FACS, ICC, IP 宿主: 小鼠 Monoclonal CS9 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 WB 宿主: 小鼠 Monoclonal 44-1 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 107-156) antibodyCYBA 适用: 人, 小鼠, 大鼠, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 117-145), (C-Term) antibodyCYBA 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31767 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (Middle Region) antibodyCYBA 适用: 人, 小鼠, 大鼠, Pig, 犬, 马, Cow, 兔, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 124-153), (C-Term) antibodyCYBA 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, 0.09 % NaN3, 1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8 °C.
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- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
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别名
- Cytochrome B-245 Light Chain
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背景
- The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome b558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
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基因ID
- 1535
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NCBI登录号
- NP_000092
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UniProt
- P13498
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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