CYBA 抗体
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北京 101111
Quick Overview for CYBA 抗体 (ABIN1449193)
抗原
See all CYBA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with an extracellular epitope of gp91phox. The antibody recognizes the epitope in the native conformation or after treatment with guanidine or urea, but SDS treatment will abolish antibody binding.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein-A agarose
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免疫原
- Human cytochrome b rich fraction
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亚型
- IgG1
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anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 21-120) antibody
CYBA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 128-195) antibodyCYBA 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (N-Term) antibodyCYBA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 WB, ELISA, IF, IHC (fro), FACS, ICC, IP 宿主: 小鼠 Monoclonal CS9 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 WB 宿主: 小鼠 Monoclonal 44-1 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 107-156) antibodyCYBA 适用: 人, 小鼠, 大鼠, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 117-145), (C-Term) antibodyCYBA 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31767 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (Middle Region) antibodyCYBA 适用: 人, 小鼠, 大鼠, Pig, 犬, 马, Cow, 兔, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 124-153), (C-Term) antibodyCYBA 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
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别名
- Cytochrome B-245 Light Chain
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背景
- The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome B558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
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基因ID
- 1535
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NCBI登录号
- NP_000092
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UniProt
- P13498
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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