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ATP1A1 抗体

The 小鼠 单克隆 anti-ATP1A1 antibody (Clone 9A7) (ABIN1449189) specifically detects ATP1A1 in WB 和 IF. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN1449189
发货至: 中国
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Quick Overview for ATP1A1 抗体 (ABIN1449189)

抗原

See all ATP1A1 抗体
ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

适用

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  • 1
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人, 大鼠

宿主

  • 96
  • 8
  • 3
  • 1
  • 1
小鼠

克隆类型

  • 96
  • 13
单克隆

标记

  • 63
  • 4
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  • 1
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This ATP1A1 antibody is un-conjugated

应用范围

  • 97
  • 37
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  • 17
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  • 7
  • 5
Western Blotting (WB), Immunofluorescence (IF)

克隆位点

9A7
  • 特异性

    This antibody reacts with human Na+/K+ ATPase α subunit.

    纯化方法

    Protein A agarose

    免疫原

    Chicken brain synaptic membrane

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

    别名

    ATP1A1

    背景

    Na+/K+-ATPase is an integral membrane protein complex that is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. Na+/K+-ATPase hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+. The Na+/K+-ATPase consists of a large transmembrane catalytic subunit, termed the a subunit, and an associated smaller glycoprotein, termed the ß subunit, that appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane. There are three isoforms of the a subunit (a-1, -2, and -3) and two isoforms of the ß subunit (ß-1 and -2) encoded by two multigene families. The a-1 and ß mRNAs are present in all cell types examined, whereas the a-2 and a-3 mRNAs exhibit a more restricted pattern of cell-specific expression. The a subunit protein has been found in kidney, brain (both neuronal and non-neuronal cells), heart, and to a lesser extent liver, skeletal and smooth muscle.Synonyms: Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1

    分子量

    80 kDa

    基因ID

    476

    NCBI登录号

    NP_000692

    UniProt

    P05023

    途径

    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process
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