ATP1A1 抗体
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Quick Overview for ATP1A1 抗体 (ABIN1449189)
抗原
See all ATP1A1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with human Na+/K+ ATPase α subunit.
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纯化方法
- Protein A agarose
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免疫原
- Chicken brain synaptic membrane
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))
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别名
- ATP1A1
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背景
- Na+/K+-ATPase is an integral membrane protein complex that is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. Na+/K+-ATPase hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+. The Na+/K+-ATPase consists of a large transmembrane catalytic subunit, termed the a subunit, and an associated smaller glycoprotein, termed the ß subunit, that appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane. There are three isoforms of the a subunit (a-1, -2, and -3) and two isoforms of the ß subunit (ß-1 and -2) encoded by two multigene families. The a-1 and ß mRNAs are present in all cell types examined, whereas the a-2 and a-3 mRNAs exhibit a more restricted pattern of cell-specific expression. The a subunit protein has been found in kidney, brain (both neuronal and non-neuronal cells), heart, and to a lesser extent liver, skeletal and smooth muscle.Synonyms: Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1
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分子量
- 80 kDa
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基因ID
- 476
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NCBI登录号
- NP_000692
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UniProt
- P05023
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途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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