CD44 抗体
Quick Overview for CD44 抗体 (ABIN1449180)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with CD44 antigen.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein A agarose
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免疫原
- MML-1 human leukemia cells
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亚型
- IgG2a
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anti-CD44 (CD44) antibody
CD44 适用: 人, 小鼠 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E2F3 unconjugated
anti-CD44 (CD44) antibodyKO Validated CD44 适用: 人 WB, IF, IHC (p), IP, IHC (fro), ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 148-247) antibodyCD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 21-220) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 6G2D2 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition 宿主: 小鼠 Monoclonal MEM-85 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人, 犬, Pig FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-263 unconjugated
anti-CD44 (CD44) (AA 36-194) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7F4F1 unconjugated
anti-CD44 (CD44) (AA 21-259) antibodyCD44 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, ELISA, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 35-300) antibodyCD44 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 1-361) antibodyCD44 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD44
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别名
- CD44
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背景
- CD44 (H-CAM/Pgp-1/Hermes antigen/ECMR-III/HUTCH-I) is a highly glycosylated transmembrane protein expressed by lymphocytes, fibroblasts, smooth muscle cells, and epithelial cells. CD44 functions as lymphocyte adhesion molecule, acting as a matrix receptor that mediates cell adhesion to the extracellular matrix. CD44 is also involved in T-lymphocyte activation, lymphocyte homing, cell migration, and hemopoiesis. Expression of CD44 on the cell surface changes profoundly during tumor metastasis, and the transition from non-metastatic to metastatic tumor cell variants is associated with expression of CD44 variants (CD44v's), making CD44 a potential cancer marker. CD44 has a predicted molecular weight of 85-90 kDa, but glycosylation can increase the apparent to ~200 kDa.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1
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基因ID
- 960
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NCBI登录号
- NP_000601
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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