RNF2 抗体
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- 抗原 See all RNF2 抗体
- RNF2 (Ring Finger Protein 2 (RNF2))
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适用
- 人, 小鼠, Hamster
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RNF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- This antibody reacts with Ring1B.
- 交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Hamster
- 纯化方法
- Protein-A Sepharose
- 免疫原
- GST fusion mouse full-length Ring1B protein
- 克隆位点
- 03-03-14
- 亚型
- IgG2b
- Top Product
- Discover our top product RNF2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- RNF2 (Ring Finger Protein 2 (RNF2))
- 别名
- RNF2 (RNF2 产品)
- 别名
- BAP-1 antibody, BAP1 antibody, DING antibody, HIPI3 antibody, RING1B antibody, RING2 antibody, AI326319 antibody, AI450156 antibody, AU019207 antibody, Ring1B antibody, dinG antibody, fa19h05 antibody, ring1b antibody, wu:fa19h05 antibody, wz4556 antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring2 antibody, ring finger protein 2 antibody, ring finger protein 2 L homeolog antibody, RNF2 antibody, Rnf2 antibody, rnf2 antibody, rnf2.L antibody
- 背景
- Polycomb-group (PcG) proteins form multimeric complexes that maintain the state of transcriptional repression of several regulatory genes during development. Ring1B/Rnf2 forms part of a protein complex containing other PcG proteins, such as Mel18, Bmi1, MBLR, MPc3, and the spliceosome protein Sap155, and these complexes associate with chromatin to regulate transcription. Ring1B may also play a role in the regulation of Hox gene expression by PcG complexes. Deletion of Ring1B activity results in gastrulation arrest and cell cycle inhibition.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B
- 基因ID
- 6045
- NCBI登录号
- NP_009143
- UniProt
- Q99496
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