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RNF2 抗体

This anti-RNF2 antibody is a 小鼠 单克隆 antibody detecting RNF2 in WB 和 IP. Suitable for 人, 小鼠 和 Hamster.
产品编号 ABIN1449179
发货至: 中国
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Quick Overview for RNF2 抗体 (ABIN1449179)

抗原

See all RNF2 抗体
RNF2 (Ring Finger Protein 2 (RNF2))

适用

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人, 小鼠, Hamster

宿主

  • 40
  • 6
  • 3
  • 1
小鼠

克隆类型

  • 31
  • 19
单克隆

标记

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This RNF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

03-03-14
  • 特异性

    This antibody reacts with Ring1B.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Hamster

    纯化方法

    Protein-A Sepharose

    免疫原

    GST fusion mouse full-length Ring1B protein

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RNF2 (Ring Finger Protein 2 (RNF2))

    别名

    RNF2

    背景

    Polycomb-group (PcG) proteins form multimeric complexes that maintain the state of transcriptional repression of several regulatory genes during development. Ring1B/Rnf2 forms part of a protein complex containing other PcG proteins, such as Mel18, Bmi1, MBLR, MPc3, and the spliceosome protein Sap155, and these complexes associate with chromatin to regulate transcription. Ring1B may also play a role in the regulation of Hox gene expression by PcG complexes. Deletion of Ring1B activity results in gastrulation arrest and cell cycle inhibition.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B

    基因ID

    6045

    NCBI登录号

    NP_009143

    UniProt

    Q99496
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