SF3B1 抗体
Quick Overview for SF3B1 抗体 (ABIN1449178)
抗原
See all SF3B1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Sap155.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Hamster
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纯化方法
- Protein A agarose
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免疫原
- Recombinant mouse Sap155
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亚型
- IgG2b
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anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibody
SF3B1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibodySF3B1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 6C7 unconjugated Recombinant Antibody
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 1-144) antibodySF3B1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 186-378) antibodySF3B1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 374-402), (N-Term) antibodySF3B1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33758 unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 98-198) antibodySF3B1 适用: 人, 小鼠 WB, IF, IP 宿主: 小鼠 Monoclonal 16 unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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别名
- SF3B1 / SAP155
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背景
- SF3 is a U2 snRNP-associated protein complex essential for spliceosome assembly and splicing catalysis of the major spliceosome. SF3 contains the Spliceosome-Associated Proteins, SAP 49, 130, 145, and 155. SAP155/Sf3b1 is an essential subunit of the U2 snRNP for mRNA splicing and has also been identified in the minor (U12-dependent) spliceosome. SAP155 interacts with the mammalian PcG (Polycomb group) proteins, Mel18 and Ring1B by the yeast two-hybrid system. SAP155 contains numerous Cdk consensus phosphorylation sites in its N terminus and is phosphorylated prior to catalytic step II of the splicing pathway. SAP155 serves as a substrate for cyclin E-cdk2 in vitro, suggesting that pre-mRNA splicing may be linked to the cell cycle machinery in mammalian cells.Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit, SAP 155, SAP-155, SF3b155, Spliceosome-associated protein 155, Splicing factor 3B subunit 1
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基因ID
- 23451
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NCBI登录号
- NP_036565
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UniProt
- O75533
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途径
- Chromatin Binding
抗原
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