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PD-L1 抗体

PD-L1 适用: 人 FACS 宿主: 小鼠 Monoclonal J105 unconjugated
产品编号 ABIN1449173
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This PD-L1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with human PD-1.
    纯化方法
    Protein-A agarose
    免疫原
    Human PD-1 Fc fusion protein
    克隆位点
    J105
    亚型
    IgG1
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    CD274 / PDL1 (PD-L1 产品)
    背景
    Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen-presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
    基因ID
    29126
    NCBI登录号
    NP_054862
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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