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PD-L1 抗体 (Extracellular Domain) (PE)

This anti-PD-L1 antibody is a 小鼠 单克隆 antibody detecting PD-L1 in FACS. Suitable for 人.
产品编号 ABIN1449172
发货至: 中国

Quick Overview for PD-L1 抗体 (Extracellular Domain) (PE) (ABIN1449172)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

  • 273
  • 142
  • 72
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宿主

  • 153
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  • 20
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  • 1
小鼠

克隆类型

  • 203
  • 122
  • 7
单克隆

标记

  • 158
  • 26
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  • 9
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This PD-L1 antibody is conjugated to PE

应用范围

  • 194
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  • 1
  • 1
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Flow Cytometry (FACS)

克隆位点

J110
  • 抗原表位

    • 72
    • 29
    • 16
    • 15
    • 14
    • 11
    • 11
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    • 7
    • 7
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    • 2
    • 2
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    • 1
    • 1
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    Extracellular Domain

    特异性

    This antibody reacts with human PD-1.

    纯化方法

    Protein A agarose

    免疫原

    Fusion protein of the extracellular domain of human PD-1 and the constant region of human gamma1 heavy chain

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS, 0.09 % NaN3, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8 °C.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    CD274 / PDL1

    背景

    Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune diseases and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1

    基因ID

    29126

    NCBI登录号

    NP_054862

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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