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PD-L1 抗体

This 小鼠 单克隆 anti-PD-L1 antibody (Clone J110) specifically detects PD-L1 in WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1449170
发货至: 中国
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中国
北京 101111
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Quick Overview for PD-L1 抗体 (ABIN1449170)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

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小鼠

克隆类型

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单克隆

标记

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This PD-L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

J110
  • 特异性

    This antibody reacts with human PD-1.

    纯化方法

    Protein-A Sepharose

    免疫原

    Human PD-1-Fc fusion protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    CD274 / PDL1

    背景

    Human PD-1 (programmed death-1) is a 55KDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen-presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1

    基因ID

    29126

    NCBI登录号

    NP_054862

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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