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IFI35 抗体 (PE)

The PE-conjugated 兔 多克隆 anti-IFI35 antibody (ABIN1437237) specifically detects IFI35 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1437237
发货至: 中国
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Quick Overview for IFI35 抗体 (PE) (ABIN1437237)

抗原

See all IFI35 抗体
IFI35 (Interferon-Induced Protein 35 (IFI35))

适用

人, 小鼠, 大鼠

宿主

  • 28
  • 9

克隆类型

  • 31
  • 6
多克隆

标记

  • 25
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFI35 antibody is conjugated to PE

应用范围

  • 27
  • 13
  • 13
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IFI35

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IFI35 (Interferon-Induced Protein 35 (IFI35))

    别名

    IFI35

    背景

    Synonyms: I 35, i-35, I35, P 35, P35, IN35, IN35_HUMAN, Interferon induced 35 kDa protein, Interferon-induced 35 kDa protein.

    Background: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events.

    基因ID

    3430
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