HECA 抗体 (PE-Cy5.5)
Quick Overview for HECA 抗体 (PE-Cy5.5) (ABIN1437230)
抗原
See all HECA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HECA
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亚型
- IgG
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anti-Headcase Homolog (HECA) (AA 434-543) antibody
HECA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Headcase Homolog (HECA) (AA 260-310) antibodyHECA 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Headcase Homolog (HECA) (AA 359-408) antibodyHECA 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HECA (Headcase Homolog (HECA))
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别名
- HECA
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背景
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Synonyms: HDCL, Gm869, HDC, HDC_HUMAN, Headcase homolog Drosophila, Headcase protein homolog, HECA, hHDC.
Background: HECA, also known as headcase homolog, HDC, HDCL or HHDC, is a 543 amino acid mammalian homolog of the Drosophila headcase protein, a highly basic, cytplasmic peptide that plays a role in mitotic re-entry during adult morphogenesis. Expressed in a variety of tissues with highest expression in thymus, spleen and heart, HECA is thought to play a role in the development of epithelial tube networks in lung tissue and may also be involved in the pathogenesis of lung cancer. The gene encoding HECA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
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分子量
- 59kDa
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基因ID
- 51696
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UniProt
- Q9UBI9
抗原
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