SLITRK2 抗体 (PE-Cy5.5)
Quick Overview for SLITRK2 抗体 (PE-Cy5.5) (ABIN1429013)
抗原
See all SLITRK2 抗体适用
宿主
克隆类型
标记
应用范围
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SLITRK2
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亚型
- IgG
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anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (AA 79-111) antibody
SLITRK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (AA 301-315), (Extracellular) antibodySLITRK2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (Middle Region) antibodySLITRK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (C-Term) antibodySLITRK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
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别名
- SLITRK2
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背景
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Synonyms: CXorf2, KIAA1854, SLIK2_HUMAN, SLIT and NTRK like protein 2, SLIT and NTRK-like protein 2, SLITL1, SLITRK 2, Slitrk2.
Background: SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.
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分子量
- 93kDa
抗原
-
