ABCA7 抗体 (PE-Cy7)
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北京 101111
Quick Overview for ABCA7 抗体 (PE-Cy7) (ABIN1425219)
抗原
See all ABCA7 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ABCA7
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亚型
- IgG
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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) (Middle Region) antibody
ABCA7 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) antibodyABCA7 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) antibodyABCA7 适用: 小鼠 WB, FACS 宿主: 大鼠 Monoclonal 7A1-144 unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) (N-Term) antibodyABCA7 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
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别名
- ABCA7
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背景
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Synonyms: ABC transporter ABCA7, ABC transporter member 7, ABCA SSN, ABCX, ATP binding cassette sub family A ABC1 member 7, ATP binding cassette sub family A member 7, ATP binding Cassette Transporter A7,FLJ40025, Macrophage ABC transporter, ABCA7_HUMAN.
Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
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分子量
- 237kDa
抗原
-
