CLNS1A 抗体 (HRP)
Quick Overview for CLNS1A 抗体 (HRP) (ABIN1422904)
抗原
See all CLNS1A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CLNS1A/pICln
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亚型
- IgG
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anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) antibody
CLNS1A 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2187C2a unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 1-237) antibodyCLNS1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 189-216), (C-Term) antibodyCLNS1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19567 unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 148-176) antibodyCLNS1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19566 unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (C-Term) antibodyCLNS1A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (C-Term) antibodyCLNS1A 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 138-187) antibodyCLNS1A 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (C-Term) antibodyCLNS1A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (C-Term) antibodyCLNS1A 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))
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别名
- CLNS1A
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背景
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Synonyms: nucleotide sensitive 1A, Chloride channel, Chloride channel nucleotide sensitive 1A, Chloride channel regulatory protein, Chloride conductance regulatory protein ICln, Chloride ion current inducer protein, ClCI, CLNS 1A, Clns1a, CLNS1B, ICln, ICln, ICLN_HUMAN, Methylosome subunit pICln, Reticulocyte pICln
Background: The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs. This process is mediated by the survival of motor neuron (SMN) protein, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs). sDMA modification of Sm proteins is catalyzed by the methylosome, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, while pICln binds the Sm domains. pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core. pICln is a highly conserved, ubiquitously expressed protein that localizes primarily to the cytoplasm, and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome. The gene encoding human pICln maps to chromosome 11q14.1.
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基因ID
- 1207
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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