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- 抗原 See all CLNS1A 抗体
- CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLNS1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from C-terminal of Human CLNS1A.
- 亚型
- IgG
- Top Product
- Discover our top product CLNS1A Primary Antibody
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anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 1-237) antibody
CLNS1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 189-216), (C-Term) antibodyCLNS1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19567 unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 148-176) antibodyCLNS1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19566 unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (C-Term) antibodyCLNS1A 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (AA 138-187) antibodyCLNS1A 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Hamster, 猴, Bat, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) (C-Term) antibodyCLNS1A 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))
- 别名
- CLNS1A (CLNS1A 产品)
- 别名
- CLCI antibody, CLNS1B antibody, ICln antibody, 2610036D06Rik antibody, 2610100O04Rik antibody, Clci antibody, Clcni antibody, ICLN antibody, Icln antibody, pICln antibody, clci antibody, clns1b antibody, icln antibody, pIcIn antibody, chloride nucleotide-sensitive channel 1A antibody, chloride channel, nucleotide-sensitive, 1A antibody, chloride channel, nucleotide-sensitive, 1A L homeolog antibody, CLNS1A antibody, Clns1a antibody, clns1a.L antibody, clns1a antibody
- 背景
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Background: Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also indirectly participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
Buyse G., Biochem. Biophys. Res. Commun. 218:822-827(1996).
Anquita J., Biochem. Biophys. Res. Commun. 208:89-95(1995).
Lamb F.S., Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases.Aliases: Chloride channel antibody, Chloride channel nucleotide sensitive 1A antibody, Chloride channel regulatory protein antibody, Chloride conductance regulator, volume sensitive antibody, Chloride conductance regulatory protein ICln antibody, Chloride ion current inducer protein antibody, ClCI antibody, CLNS 1A antibody, Clns1a antibody, CLNS1B antibody, I(Cln) antibody, ICln antibody, ICLN_HUMAN antibody, Methylosome subunit pICln antibody, nucleotide sensitive 1A antibody, Reticulocyte pICln antibody, Reticulocyte protein ICln antibody
- UniProt
- P54105
- 途径
- Ribonucleoprotein Complex Subunit Organization
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