HEY2 抗体 (Cy5.5)
Quick Overview for HEY2 抗体 (Cy5.5) (ABIN1420717)
抗原
See all HEY2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human HEY2
-
亚型
- IgG
-
-
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (AA 1-110) antibody
HEY2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (N-Term) antibodyHEY2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (AA 65-91), (N-Term) antibodyHEY2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB24640 unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) antibodyHEY2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (AA 1-337) antibodyHEY2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (C-Term) antibodyHEY2 适用: 人, 斑马鱼, 豚鼠, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (AA 1-100) antibodyHEY2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) (AA 295-322), (C-Term) antibodyHEY2 适用: 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IF(IHC-P) 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
-
别名
- HEY2
-
背景
-
Synonyms: bHLHb32, Cardiovascular helix loop helix factor 1, Cardiovascular helix-loop-helix factor 1, CHF1, Class B basic helix-loop-helix protein 32, GRIDLOCK, GRL, Hairy and enhancer of split related 2, Hairy and enhancer of split-related protein 2, Hairy related transcription factor 2, Hairy-related transcription factor 2, Hairy/enhancer-of-split related with YRPW mot protein 2, hCHF1, HERP, HERP1, HES related repressor protein 1, HES-related repressor protein 2, HESR-2, HESR2, HEY2, HEY2_HUMAN, hHRT2, HRT-2, HRT2, Protein gridlock homolog.
Background: The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
-
基因ID
- 23493
-
途径
- Regulation of Muscle Cell Differentiation
抗原
-
