BMP10 抗体 (AA 350-400) (HRP)
Quick Overview for BMP10 抗体 (AA 350-400) (HRP) (ABIN1420636)
抗原
See all BMP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BMP10
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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别名
- BMP10
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背景
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Synonyms: Bone morphogenetic protein 1, BMP-1, BMP1
Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
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基因ID
- 27302
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UniProt
- O95393
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途径
- Hormone Activity, Regulation of Muscle Cell Differentiation
抗原
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