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BMP10 抗体 (AA 350-400) (Cy7)

This anti-BMP10 antibody is a 兔 多克隆 antibody detecting BMP10 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1420634
发货至: 中国

Quick Overview for BMP10 抗体 (AA 350-400) (Cy7) (ABIN1420634)

抗原

See all BMP10 抗体
BMP10 (Bone Morphogenetic Protein 10 (BMP10))

适用

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人, 小鼠, 大鼠

宿主

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  • 16
  • 1
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克隆类型

  • 59
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多克隆

标记

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This BMP10 antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 350-400

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BMP10

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BMP10 (Bone Morphogenetic Protein 10 (BMP10))

    别名

    BMP10

    背景

    Synonyms: Bone morphogenetic protein 1, BMP-1, BMP1

    Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

    基因ID

    27302

    UniProt

    O95393

    途径

    Hormone Activity, Regulation of Muscle Cell Differentiation
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