MTA2 抗体 (Cy5)
Quick Overview for MTA2 抗体 (Cy5) (ABIN1420590)
抗原
See all MTA2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MTA2
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亚型
- IgG
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anti-Metastasis Associated 1 Family, Member 2 (MTA2) antibody
MTA2 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 60-180) antibodyMTA2 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, Cow, 马, 兔, 山羊, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 1-394) antibodyMTA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 516-544), (C-Term) antibodyMTA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20031 unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 129-178) antibodyMTA2 适用: 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 398-447) antibodyMTA2 适用: 人, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 380-429) antibodyMTA2 适用: 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, Pig, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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别名
- MTA2
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背景
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Synonyms: Mata1l1, Metastasis associated 1 family member 2, Metastasis associated 1 like 1, Metastasis associated gene 1 like 1, Metastasis associated gene family member 2, Metastasis associated protein 2, Metastasis associated protein MTA 2, Metastasis associated protein MTA2, Mmta2, MTA1 L1 protein, MTA1-L1 protein, MTA1L1, MTA1L1: metastasis-associated 1-like 1, P53 target protein in deacetylase complex, PID, MTA2_HUMAN.
Background: MTA1 is a component of the NURD (nucleosome remodeling and histone deacetylation) complex, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity. MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin. Structurally, MTA1 contains a single SH3-binding motif and a zinc finger domain, along with a region similar to the co-repressor protein N-Cor. MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis. Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, gastrointestinal and breast carcinomas. Elevation of MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, increase mammary cell motility and potentiate growth, and therefore may be an indicator for assessing the potential malignancies of various tumors. A similar protein, MTA2, also designated MTA1-L1 (MTA1-like protein 1), shares more than 55 % sequence homology with MTA1 and is ubiquitously expressed.
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基因ID
- 9219
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途径
- Chromatin Binding
抗原
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