SPO11 抗体 (HRP)
Quick Overview for SPO11 抗体 (HRP) (ABIN1419808)
抗原
See all SPO11 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SPO11
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亚型
- IgG
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anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 291-395) antibody
SPO11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 1-358) antibodySPO11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 28-109) antibodySPO11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 1-358) antibodySPO11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (AA 110-159) antibodySPO11 适用: 人, Cow, 犬, 豚鼠, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (Internal Region) antibodyVerified SPO11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11) (N-Term) antibodySPO11 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
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别名
- SPO11
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背景
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Synonyms: Meiotic recombination protein SPO 11, Meiotic recombination protein SPO11, MGC39953, SPO 11, SPO11 meiotic protein covalently bound to DSB homolog, SPO11 meiotic protein covalently bound to DSB like, SPO11_HUMAN.
Background: Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
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基因ID
- 23626
抗原
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