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Dihydrofolate Reductase 抗体 (HRP)

This anti-Dihydrofolate Reductase antibody is a 兔 多克隆 antibody detecting Dihydrofolate Reductase in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN1418464
发货至: 中国

Quick Overview for Dihydrofolate Reductase 抗体 (HRP) (ABIN1418464)

抗原

See all Dihydrofolate Reductase (DHFR) 抗体
Dihydrofolate Reductase (DHFR)

适用

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宿主

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克隆类型

  • 43
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多克隆

标记

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This Dihydrofolate Reductase antibody is conjugated to HRP

应用范围

  • 34
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 纯化方法

    purified by Protein A

    免疫原

    KLH conjugated synthetic peptide derived from human DHFR

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 µg/µL

    缓冲液

    Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.

    储存液

    Gentamicin sulfate

    储存条件

    4 °C

    储存方法

    Store at 4 °C for 12 months

    有效期

    12 months
  • 抗原

    Dihydrofolate Reductase (DHFR)

    别名

    DHFR

    背景

    DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.

    分子量

    21kDa

    基因ID

    1719

    HGNC

    0

    途径

    Mitotic G1-G1/S Phases
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