CDC14A 抗体 (AA 51-150) (Cy5)
Quick Overview for CDC14A 抗体 (AA 51-150) (Cy5) (ABIN1417890)
抗原
See all CDC14A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Cdc14A
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亚型
- IgG
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anti-CDC14 Cell Division Cycle 14 Homolog A (CDC14A) (AA 431-530) antibody
CDC14A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-CDC14 Cell Division Cycle 14 Homolog A (CDC14A) (AA 431-530) antibodyCDC14A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-CDC14 Cell Division Cycle 14 Homolog A (CDC14A) antibodyCDC14A 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB7269 unconjugated
anti-CDC14 Cell Division Cycle 14 Homolog A (CDC14A) (AA 1-594) antibodyCDC14A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
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别名
- Cdc14A
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背景
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Synonyms: CDC 10, Cdc 14, Cdc 14A, Cdc 14A1, Cdc 14A2, CDC10, Cdc14, CDC14 cell division cycle 14 homolog A, CDC14 homolog A, Cdc14A1, Cdc14A2, Cell division cycle 14 homolog A, Dual specicity protein phosphatase CDC 14A, Dual specicity protein phosphatase CDC14A, hCDC14, CC14A_HUMAN.
Background: In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells. Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation.
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基因ID
- 8556
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UniProt
- Q9UNH5
抗原
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