CDC14A 抗体 (AA 51-150)
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- 抗原 See all CDC14A 抗体
- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
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抗原表位
- AA 51-150
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC14A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Cdc14A
- 亚型
- IgG
- Top Product
- Discover our top product CDC14A Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
- 别名
- Cdc14A (CDC14A 产品)
- 别名
- cdc14 antibody, hCDC14 antibody, xcdc14a antibody, A830059A17Rik antibody, CDC14A2 antibody, CDC14a1 antibody, Cdc14 antibody, CDC14A antibody, zgc:63654 antibody, cell division cycle 14A antibody, Dual specificity protein phosphatase CDC14A antibody, dual specificity protein phosphatase CDC14A antibody, cell division cycle 14A L homeolog antibody, CDC14 cell division cycle 14A antibody, cell division cycle 14Aa antibody, CDC14A antibody, TVAG_168700 antibody, TVAG_479730 antibody, TVAG_362610 antibody, TVAG_490830 antibody, GL50803_9270 antibody, CMU_014610 antibody, cdc14a.L antibody, Cdc14a antibody, cdc14a antibody, cdc14aa antibody
- 背景
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Synonyms: CDC 10, Cdc 14, Cdc 14A, Cdc 14A1, Cdc 14A2, CDC10, Cdc14, CDC14 cell division cycle 14 homolog A, CDC14 homolog A, Cdc14A1, Cdc14A2, Cell division cycle 14 homolog A, Dual specicity protein phosphatase CDC 14A, Dual specicity protein phosphatase CDC14A, hCDC14, CC14A_HUMAN.
Background: In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells. Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation.
- 基因ID
- 8556
- UniProt
- Q9UNH5
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