RENT1/UPF1 抗体 (AA 301-450) (Cy5)
Quick Overview for RENT1/UPF1 抗体 (AA 301-450) (Cy5) (ABIN1417626)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-450
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预测反应
- Human,Mouse,Rat,Dog,Cow,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RENT1/hUPF1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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别名
- RENT1/hUPF1
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背景
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Synonyms: ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, HUPF 1, HUPF1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1_HUMAN, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Framesht 1, Up framesht mutation 1 homolog S. cerevisiae, Up framesht mutation 1 homolog, Up framesht suppressor 1 homolog, Up-framesht mutation 1 homolog S. cerevisiae, Up-framesht suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, UPF1.
Background: In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability (13). Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase.
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基因ID
- 5976
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途径
- SARS-CoV-2 Protein Interactome
抗原
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