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OSTM1 抗体 (AA 21-120) (HRP)

This 兔 多克隆 antibody specifically detects OSTM1 in WB, ELISA, IHC (fro) 和 IHC (p). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1417312
发货至: 中国
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Quick Overview for OSTM1 抗体 (AA 21-120) (HRP) (ABIN1417312)

抗原

See all OSTM1 抗体
OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))

适用

  • 34
  • 21
  • 21
  • 3
人, 大鼠, 小鼠

宿主

  • 37
  • 1

克隆类型

  • 37
  • 1
多克隆

标记

  • 16
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OSTM1 antibody is conjugated to HRP

应用范围

  • 38
  • 17
  • 13
  • 13
  • 10
  • 7
  • 6
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OSTM1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))

    别名

    OSTM1

    背景

    Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201

    Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.

    基因ID

    28962

    UniProt

    Q86WC4
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