OSTM1 抗体 (AA 21-120)
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- 抗原 See all OSTM1 抗体
- OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
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抗原表位
- AA 21-120
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OSTM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human OSTM1
- 亚型
- IgG
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anti-Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) (AA 183-282) antibody
OSTM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) (AA 124-277) antibodyOSTM1 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) (AA 1-334) antibodyOSTM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) (AA 32-284) antibodyOSTM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Osteopetrosis Associated Transmembrane Protein 1 (OSTM1) (AA 120-251) antibodyOSTM1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
- 别名
- OSTM1 (OSTM1 产品)
- 背景
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Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201
Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.
- 基因ID
- 28962
- UniProt
- Q86WC4
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