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LIG4 抗体 (AA 51-150) (HRP)

This anti-LIG4 antibody is a 兔 多克隆 antibody detecting LIG4 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1413950
发货至: 中国

Quick Overview for LIG4 抗体 (AA 51-150) (HRP) (ABIN1413950)

抗原

See all LIG4 抗体
LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

适用

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宿主

  • 62
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克隆类型

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多克隆

标记

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This LIG4 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 51-150

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DNA Ligase IV

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

    别名

    DNA Ligase IV/LIG4

    背景

    Synonyms: LIG4S, DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4

    Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

    基因ID

    3981

    UniProt

    P49917

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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