Metabotropic Glutamate Receptor 3 抗体 (AA 365-460) (HRP)
Quick Overview for Metabotropic Glutamate Receptor 3 抗体 (AA 365-460) (HRP) (ABIN1412540)
抗原
See all Metabotropic Glutamate Receptor 3 (GRM3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 365-460
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 3
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
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别名
- MGLUR3
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背景
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Synonyms: G protein coupled receptor family C group 1 member C, GLUR 3, GLUR3, GLUR3, Glutamate metabotropic receptor 3, Glutamate receptor metabotropic 3, GPRC1C, GRM 3, GRM3, GRM3_HUMAN, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 3 precursor, mGlu 3, MGlu3, MGlu3, MGLUR 3, MGLUR3.
Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
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途径
- cAMP Metabolic Process, Synaptic Membrane
抗原
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