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CRBN 抗体 (AA 210-288) (Cy7)

This anti-CRBN antibody is a 兔 多克隆 antibody detecting CRBN in IF (cc) 和 IF (p). Suitable for 小鼠 和 大鼠.
产品编号 ABIN1410810
发货至: 中国

Quick Overview for CRBN 抗体 (AA 210-288) (Cy7) (ABIN1410810)

抗原

See all CRBN 抗体
CRBN (Cereblon (CRBN))

适用

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  • 20
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  • 3
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  • 2
  • 1
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  • 1
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  • 1
小鼠, 大鼠

宿主

  • 32
  • 3

克隆类型

  • 34
  • 1
多克隆

标记

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  • 1
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This CRBN antibody is conjugated to Cy7

应用范围

  • 20
  • 12
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  • 9
  • 9
  • 7
  • 4
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  • 3
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-288

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CRBN

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CRBN (Cereblon (CRBN))

    别名

    CRBN

    背景

    Synonyms: Cereblon, DKFZp781K0715, MGC27358, MRT2A, OTTHUMP00000209555, piL, Protein cereblon, Protein x 0001, 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, CRBN_HUMAN.

    Background: CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.

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