CALHM1 抗体 (AA 161-260) (Cy7)
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北京 101111
Quick Overview for CALHM1 抗体 (AA 161-260) (Cy7) (ABIN1410372)
抗原
See all CALHM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-260
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预测反应
- Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CALHM1/FAM26C
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亚型
- IgG
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anti-Calcium Homeostasis Modulator 1 (CALHM1) (N-Term) antibody
CALHM1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibodyCALHM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibodyCALHM1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 295-344) antibodyCALHM1 适用: 人, 大鼠, 小鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (Intracellular) antibodyCALHM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (Intracellular) antibody (Atto 594)CALHM1 适用: 人 IHC, IF, IC 宿主: 兔 Polyclonal Atto 594
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
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别名
- CALHM1/FAM26C
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背景
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Synonyms: CAHM1_HUMAN, Calcium homeostasis modulator 1, Calcium homeostasis modulator protein 1, CALHM1, FAM26C, Family with sequence similarity 26, member C, MGC39514, MGC39617, Protein FAM26C.
Background: CALHM1 is a 346 amino acid multi-pass endoplasmic reticulum membrane protein that belongs to the FAM26 family. CALHM1 co-localizes with GRP 78 to the endoplasmic reticulum. Predominantly expressed in adult brain, CALHM1 may be a pore-forming ion channel that controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration in the cell. It is suggested that CALHM1 regulates amyloid precursor protein proteolysis and aggregated amyloid-beta peptides levels in a Ca2+ dependent manner. CALHM1 homomultimerizes and shares strong sequence similarities with the selectivity filter of the NMDA receptor, which generates a large Ca2+ conductance across the plasma membrane. CALHM1 may be a potential factor involved in the pathogenesis of Alzheimer's disease.
抗原
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