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ABLIM1 抗体 (AA 681-778) (Cy5.5)

This anti-ABLIM1 antibody is a 兔 多克隆 antibody detecting ABLIM1 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1409231
发货至: 中国

Quick Overview for ABLIM1 抗体 (AA 681-778) (Cy5.5) (ABIN1409231)

抗原

See all ABLIM1 抗体
ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ABLIM1 antibody is conjugated to Cy5.5

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 681-778

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ABLIM1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))

    别名

    ABLIM1

    背景

    Synonyms: ABLIM 1, ABLIM, abLIM-1, ABLIM-L, ABLIM-M, ABLIM-S, ABLIM1, ABLM1_HUMAN, Actin binding double zinc finger protein, Actin binding LIM protein 1, Actin binding LIM protein family member 1, Actin-binding double zinc finger protein, Actin-binding double zinc finger protein, Actin-binding LIM protein 1, Actin-binding LIM protein family member 1, DKFZp781D0148, FLJ14564, KIAA0059, LIM actin binding protein 1, LIMAB 1, LIMAB1, Limatin, RGD1565768, RP11-317F20.1.

    Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

    基因ID

    3983
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