RIC8A 抗体 (AA 301-400) (Cy3)
Quick Overview for RIC8A 抗体 (AA 301-400) (Cy3) (ABIN1408671)
抗原
See all RIC8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RIC8A
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亚型
- IgG
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anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 462-534) antibody
RIC8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyRIC8A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyVerified RIC8A 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 143-192) antibodyRIC8A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (N-Term) antibodyRIC8A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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别名
- RIC8A
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背景
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Synonyms: Protein Ric-8A, resistance to inhibitors of cholinesterase 8 homolog A C. elegans, RIC8, RIC8A, RIC8A_HUMAN, synembryn, Synembryn-A, MGC104517, MGC131931, MGC148073, MGC148074.
Background: The Ras superfamily of GTPases can be subdivided into the Ras, Rho/Rac, Sar, Rab, Arf, Rap and Ran subfamilies, all of which control multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form. This activation is catalyzed by guanine nucleotide exchange factors (GEFs). RIC-8A (resistance to inhibitors of cholinesterase 8 homolog A), also known as RIC8 or Synembryn-A, is a 530 amino acid cytoplasmic protein that can activate several G-alpha proteins, including G?i-1, G?q and G?o. Functioning as a guanine nucleotide exchange factor, RIC-8A binds to GDP-associated substrates and exchanges bound GDP for free GTP. Via its ability to stimulate protein function, RIC-8A plays a role in regulating mitotic movement and may be involved in receptor-mediated ERK activation. RIC-8A is expressed as three isoforms due to alternative splicing events.
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
抗原
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