OTUB1 抗体 (AA 51-150) (Cy3)
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- 抗原 See all OTUB1 抗体
- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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抗原表位
- AA 51-150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OTUB1 antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human OTUB1
- 亚型
- IgG
- Top Product
- Discover our top product OTUB1 Primary Antibody
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anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibody
OTUB1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 5B8 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5F7 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (Internal Region) antibodyOTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 1-220) antibodyOTUB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 2-201) antibodyOTUB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 1-271) antibodyOTUB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (Center) antibodyOTUB1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
- 别名
- OTUB1 (OTUB1 产品)
- 背景
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Synonyms: Deubiquitinating enzyme OTUB1, hOTU1, OTB1, OTU domain containing ubiquitin aldehyde binding protein 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, OTU1, Otub1, OTUB1_HUMAN, Otubain 1, Otubain-1, Ubiquitin specic processing protease OTUB1, Ubiquitin thioesterase OTUB1, Ubiquitin-specic-processing protease OTUB1.
Background: OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases. Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, thereby preventing protein degradation and playing an important role in protein turnover. OTUB1 interacts with GRAIL and, via this interaction, plays a role in the regulation and the induction of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens. Due to its interaction with GRAIL, OTUB1 is an important regulator of immune responses in secondary lymphoid organs.
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