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OLIG2 抗体 (AA 81-180) (Cy5.5)

This anti-OLIG2 antibody is a 兔 多克隆 antibody detecting OLIG2 in FACS, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN1407725
发货至: 中国

Quick Overview for OLIG2 抗体 (AA 81-180) (Cy5.5) (ABIN1407725)

抗原

See all OLIG2 抗体
OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

适用

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人, 大鼠

宿主

  • 71
  • 24
  • 1

克隆类型

  • 62
  • 34
多克隆

标记

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This OLIG2 antibody is conjugated to Cy5.5

应用范围

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Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 13
    • 9
    • 7
    • 6
    • 4
    • 4
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-180

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OLIG2

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

    别名

    OLIG2

    背景

    Synonyms: Basic domain helix loop helix protein class B 1, Basic helix loop helix protein class B 1, bHLHB1, bHLHe19, Class B basic helix loop helix protein 1, Class B basic helix-loop-helix protein 1, class E basic helix loop helix protein 19, Class E basic helix-loop-helix protein 19, Human protein kinase C binding protein RACK17, Olig2, OLIG2_HUMAN, Oligo2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specic bHLH transcription factor 2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C binding protein 2, Protein kinase C binding protein RACK17, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17.

    Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.

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