UVRAG 抗体 (AbBy Fluor® 350)
Quick Overview for UVRAG 抗体 (AbBy Fluor® 350) (ABIN1405461)
抗原
See all UVRAG 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human UVRAG/DHTX
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亚型
- IgG
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anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 501-699) antibody
UVRAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 375-425) antibodyUVRAG 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 601-699) antibodyUVRAG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibodyUVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (HRP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (FITC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Biotin)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (PE)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (PerCP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (APC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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别名
- UVRAG
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背景
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Synonyms: DHTX, Disrupted in heterotaxy, p63, UV radiation resistance associated, UV radiation resistance associated gene, UV radiation resistance associated gene protein, UV radiation resistance-associated gene protein, UVRAG, UVRAG_HUMAN.
Background: UVRAG, also known as p63 or DHTX, is a 699 amino acid cytoplasmic protein. UVRAG has been shown to activate the BECN1/PI 3-kinase complex, which promotes autophagy. Autophagy is the degradation of cellular proteins in the lysosomes, and when this pathway is suppressed, cell growth is deregulated. Mutations in the gene encoding UVRAG have been associated with colon cancer, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells. UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells. Ubiquitously expressed, UVRAG is found at highest levels in kidney, lung, liver and brain. UVRAG contains one C2 domain, which is thought to be involved in calcium-dependent phospholipid binding.
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基因ID
- 7405
抗原
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