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PYGB 抗体 (AbBy Fluor® 488)

This anti-PYGB antibody is a 兔 多克隆 antibody detecting PYGB in IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1402798
发货至: 中国

Quick Overview for PYGB 抗体 (AbBy Fluor® 488) (ABIN1402798)

抗原

See all PYGB (GPBB) 抗体
PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

适用

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人, 小鼠, 大鼠

宿主

  • 65
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克隆类型

  • 65
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多克隆

标记

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This PYGB antibody is conjugated to AbBy Fluor® 488

应用范围

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Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GPBB/PYGB

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

    别名

    GPBB

    背景

    Synonyms: Brain glycogen phosphorylase, Glycogen phosphorylase B, Glycogen phosphorylase brain form, Glycogen Phosphorylase Isoenzyme BB, Glycogen phosphorylase, brain form, MGC9213, Phosphorylase glycogen brain, PYGB, PYGB_HUMAN.

    Background: Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose. fructose kinase-2/fructose 2,6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2,6-bisphosphate. Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism. Its activity is regulated through either noncovalent binding of metabolites or by covalent modification. Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P. There are three genes which encode the brain, liver and muscle forms of glycogen phosphorylase, PYGB, PYGL and PYGM. Because of its fundamental role in the metabolism of glycogen, glycogen phosphorylase has been a target for the design of inhibitory compounds, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus.

    基因ID

    5834

    途径

    Cellular Glucan Metabolic Process
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