RNF20 抗体 (AbBy Fluor® 350)
Quick Overview for RNF20 抗体 (AbBy Fluor® 350) (ABIN1401675)
抗原
See all RNF20 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
 - 人, 小鼠, 大鼠
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human RNF20
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亚型
 - IgG
 
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应用备注
 - IF(IHC-P) 1:50-200
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- RNF20 (Ring Finger Protein 20 (RNF20))
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别名
 - RNF20
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背景
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Synonyms: BRE1A, BRE1 A, E3 ubiquitin-protein ligase BRE1A, hBRE1, RING finger protein 20, BRE1A_HUMAN.
Background: RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. It is recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
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基因ID
 - 56254
 
抗原
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