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MLF1 抗体 (Biotin)

This anti-MLF1 antibody (ABIN1401295) is a Rabbit Polyclonal antibody detecting MLF1 in WB, IHC (p). Suitable for Human, Mouse, Rat.
产品编号 ABIN1401295
发货至: 中国

Quick Overview for MLF1 抗体 (Biotin) (ABIN1401295)

抗原

See all MLF1 抗体
MLF1 (Myeloid Leukemia Factor 1 (MLF1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MLF1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MLF1/2/3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    MLF1 (Myeloid Leukemia Factor 1 (MLF1))

    别名

    MLF1

    背景

    Synonyms: Hls7, MLF1, MLF2, MLF3, MLF1_HUMAN, Myelodysplasia myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1, myeloid leukemia factor 1 variant 1, myeloid leukemia factor 1 variant 2, myeloid leukemia factor 1 variant 3.

    Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

    基因ID

    4291
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