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FBXW5 抗体 (Biotin)

This anti-FBXW5 antibody (ABIN1400743) is a Rabbit Polyclonal antibody detecting FBXW5 in WB, IHC (p). Suitable for Human, Mouse, Rat.
产品编号 ABIN1400743
发货至: 中国

Quick Overview for FBXW5 抗体 (Biotin) (ABIN1400743)

抗原

See all FBXW5 抗体
FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This FBXW5 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FBXW5

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

    别名

    FBXW5

    背景

    Synonyms: F box and WD 40 domain containing protein 5, F box and WD repeat domain containing 5, FBW5, FBXW5_HUMAN.

    Background: FBXW5 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW5 contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

    基因ID

    54461
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