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DIS3L2 抗体 (AbBy Fluor® 350)

This anti-DIS3L2 antibody (ABIN1400559) is a Rabbit Polyclonal antibody detecting DIS3L2 in WB, IF (p). Suitable for Human, Mouse, Rat.
产品编号 ABIN1400559
发货至: 中国

Quick Overview for DIS3L2 抗体 (AbBy Fluor® 350) (ABIN1400559)

抗原

See all DIS3L2 抗体
DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DIS3L2 antibody is conjugated to AbBy Fluor® 350

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DIS3L2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

    别名

    DIS3L2

    背景

    Synonyms: DIS3 L2, DIS3 mitotic control homolog S. cerevisiae like 2, DIS3 mitotic control homolog like 2, FLJ36974, MGC42174, DI3L2_HUMAN.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3? region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3? processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.

    基因ID

    129563

    途径

    Stem Cell Maintenance
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