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c-MYC 抗体 (pThr373) (AbBy Fluor® 350)

This anti-c-MYC antibody is a 兔 多克隆 antibody detecting c-MYC in WB 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN1399113
发货至: 中国

Quick Overview for c-MYC 抗体 (pThr373) (AbBy Fluor® 350) (ABIN1399113)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This c-MYC antibody is conjugated to AbBy Fluor® 350

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    pThr373

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human C-Myc around the phosphorylation site of Ser373

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    C-Myc

    背景

    Synonyms: MycSer373, MycS373, p-MycSer373, p-MycS373, AU016757, Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, Cellular myelocytomatosis oncogene,

    Background: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].

    基因ID

    4609

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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