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PCGF1 抗体 (AA 51-150) (Biotin)

This anti-PCGF1 antibody is a 兔 多克隆 antibody detecting PCGF1 in WB, ELISA, IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN1397136
发货至: 中国

Quick Overview for PCGF1 抗体 (AA 51-150) (Biotin) (ABIN1397136)

抗原

See all PCGF1 抗体
PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))

适用

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宿主

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克隆类型

  • 45
多克隆

标记

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This PCGF1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 51-150

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PCGF1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))

    别名

    PCGF1

    背景

    Synonyms: PCGF1_HUMAN, PCGF1, Nervous system Polycomb-1, NSPc1, Polycomb group RING finger protein 1, RING finger protein 68, RNF68.

    Background: PCGF1 is a component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. It represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). PCGF1 als promotes cell cycle progression and also enhances cell proliferation, thus it may have a positive role in tumor cell growth.

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