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Aspartate beta Hydroxylase 抗体 (AA 301-400) (AbBy Fluor® 488)

This anti-Aspartate beta Hydroxylase antibody is a 兔 多克隆 antibody detecting Aspartate beta Hydroxylase in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1395376
发货至: 中国

Quick Overview for Aspartate beta Hydroxylase 抗体 (AA 301-400) (AbBy Fluor® 488) (ABIN1395376)

抗原

See all Aspartate beta Hydroxylase (ASPH) 抗体
Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

适用

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宿主

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克隆类型

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多克隆

标记

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This Aspartate beta Hydroxylase antibody is conjugated to AbBy Fluor® 488

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 301-400

    预测反应

    Human,Mouse,Rat,Cow,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ASPH/Aspartate beta hydroxylase

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

    别名

    ASPH/Aspartate beta hydroxylase

    背景

    Synonyms: ASP beta hydroxylase, Aspartyl/asparaginyl beta hydroxylase, ASPH, BAH, CASQ2BP1, HAAH, JCTN, junctin, Peptide aspartate beta dioxygenase, ASPH_HUMAN.

    Background: Aspartyl/asparaginyl beta-hydroxylase (ASPH) is a widely-expressed type II membrane protein involved in calcium homeostasis. Located in the endoplasmic reticulum, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, using iron as a cofactor. The ASPH gene encodes 3 proteins, ASPH, Junctin, and Junctate (or Humbug), that differ significantly in their C-terminal domains. These ASPH gene products are expressed as five transcript variants that differ by their roles in calcium storage and release, hydroxylation capabilities, and tissue specificity. While all ASPH variants are expressed in skeletal muscle, only some are detected in heart, brain, pancreas, placenta, lung, liver, and kidney tissues. In the lumen of the endoplasmic reticulum, ASPH can be processed into two different forms.

    途径

    Positive Regulation of Endopeptidase Activity
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