Ensa 抗体 (AA 51-121) (FITC)
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北京 101111
Quick Overview for Ensa 抗体 (AA 51-121) (FITC) (ABIN1393358)
抗原
See all Ensa (ENSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-121
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预测反应
- Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ENSA/ARPP-19
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亚型
- IgG
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anti-Endosulfine alpha (ENSA) antibody
KO Validated ENSA 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1H7 unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) antibodyENSA 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Endosulfine alpha (ENSA) (AA 1-121) antibodyENSA 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (AA 39-66) antibodyENSA 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19622 unconjugated
anti-Endosulfine alpha (ENSA) (AA 46-74), (Middle Region) antibodyENSA 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (N-Term) antibodyENSA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endosulfine alpha (ENSA) (N-Term) antibodyENSA 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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别名
- ENSA/ARPP-19
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背景
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Synonyms: Alpha endosulfine, ARPP 19e, Endosulfine alpha, ENSA_HUMAN.
Background: Sulfonylureas are a class of drugs commonly used in the management of noninsulin-dependent diabetes mellitus. ENSA/ARPP-19, also known as ARPP-19e, is a 121 amino acid protein that localizes to the cytoplasm and belongs to the endosulfine family. ENSA/ARPP-19 is an endogenous regulator of the _-cell K(ATP) channels and reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor thereby stimulating insulin secretion by pancreatic _ cells. It is suggested that ENSA/ARPP-19 expression is decreased in brains of both Alzheimer's disease (AD) and Down's syndrome patients. Widely expressed with high levels in skeletal muscle and brain and lower levels in pancreas, ENSA/ARPP-19 is phosphorylated by PKA and exists as eight alternatively spliced isoforms. ENSA/ARPP-19 is encoded by a gene located on human chromosome 1q21.3.
抗原
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