PQBP1 抗体 (AA 185-265) (Biotin)
Quick Overview for PQBP1 抗体 (AA 185-265) (Biotin) (ABIN1393111)
抗原
See all PQBP1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 185-265
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                                            预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human PQBP1
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                                            亚型
- IgG
 
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                                            应用备注
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                        WB 1:300-5000
 IHC-P 1:200-400
 IHC-F 1:100-500
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
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                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C for 12 months.
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                                            有效期
- 12 months
 
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    - PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
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                                            别名
- PQBP1
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                                            背景
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                        Synonyms: 38 kDa nuclear protein containing a WW domain, Mental retardation, X linked 55, MRX55, MRXS3, MRXS8, Npw38, Nuclear protein containing WW domain 38 kD, Polyglutamine binding protein 1, Polyglutamine tract binding protein 1, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP 1, PQBP-1, PQBP1, PQBP1_HUMAN, RENS1, SHS, Sutherland Haan X linked mental retardation syndrome. Background: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23. 
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                                            途径
- Ribonucleoprotein Complex Subunit Organization
 抗原
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