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DUSP6 抗体 (FITC)

DUSP6 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN1391912
发货至: 中国
  • 抗原 See all DUSP6 抗体
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    适用
    • 90
    • 58
    • 51
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 78
    • 11
    • 2
    • 1
    克隆类型
    • 73
    • 19
    多克隆
    标记
    • 41
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP6 antibody is conjugated to FITC
    应用范围
    • 63
    • 35
    • 15
    • 13
    • 10
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DUSP6
    亚型
    IgG
    Top Product
    Discover our top product DUSP6 Primary Antibody
  • 应用备注
    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Li, Zhou, Ying, Shi, Cheng, Ren, Griffin, Jia, Li, Moorman, Yao: "Hepatitis C virus-induced reduction in miR-181a impairs CD4(+) T-cell responses through overexpression of DUSP6." in: Hepatology (Baltimore, Md.), (2015) (PubMed).

  • 抗原
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    别名
    Dusp6/Mkp-3 (DUSP6 产品)
    别名
    HH19 antibody, MKP3 antibody, PYST1 antibody, 1300019I03Rik antibody, MKP-3 antibody, Mkp3 antibody, wu:fd99d09 antibody, mkp3 antibody, pyst1 antibody, DUSP6 antibody, dusp6 antibody, dual specificity phosphatase 6 antibody, dual specificity phosphatase 6 L homeolog antibody, Dual specificity protein phosphatase 6 antibody, DUSP6 antibody, Dusp6 antibody, dusp6 antibody, dusp6.L antibody, dus6 antibody
    背景

    Synonyms: Dual specicity phosphatase 6, Dual specicity phosphatase 6 isoform a, Dual specicity protein phosphatase 6, Dual specicity protein phosphatase PYST1, DUS6_HUMAN, DUSP 6, DUSP 6a, Dusp6, DUSP6a, MAP kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, Mitogen-activated protein kinase phosphatase 3, MKP 3, MKP-3, MKP3, PYST 1, PYST1, Serine/threonine specic protein phosphatase.

    Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q22-q23 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.

    基因ID
    8642
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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